Search on: SRC-FAMILY KINASES 
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Descriptor English:   src-Family Kinases 
Descriptor Spanish:   Familia-src Quinasas 
Descriptor Portuguese:   Quinases da Família src 
Synonyms English:   Kinases, src
Kinases, src Protein-Tyrosine
Kinases, src Tyrosine
Protein-Tyrosine Kinases, src
Tyrosine Kinases, src
Tyrosine Kinases, src-Family
src Family Kinases
src Family Tyrosine Kinases
src Kinases
src Protein-Tyrosine Kinases
src Tyrosine Kinases
src-Family Tyrosine Kinases  
Tree Number:   D08.811.913.696.620.682.725.800
Definition English:   A PROTEIN-TYROSINE KINASE family that was originally identified by homology to the Rous sarcoma virus ONCOGENE PROTEIN PP60(V-SRC). They interact with a variety of cell-surface receptors and participate in intracellular signal transduction pathways. Oncogenic forms of src-family kinases can occur through altered regulation or expression of the endogenous protein and by virally encoded src (v-src) genes. 
See Related English:   src Homology Domains
 
History Note English:   96 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   32603 
Unique Identifier:   D019061 

Occurrence in VHL: 		 

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DeCS